Kedei, N. : rechercher sur Z-Library

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1

Neristatin 1 Provides Critical Insight into Bryostatin 1 Structure–Function Relationships

Kedei, Noemi, Kraft, Matthew B., Keck, Gary E., Herald, Cherry L., Melody, Noeleen, Pettit, George R., Blumberg, Peter M.

Journal:

Journal of Natural Products

Année:

2015

Langue:

english

Fichier:

PDF, 696 KB

english, 2015

2

Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-Ring

Baumann, David O., McGowan, Kevin M., Kedei, Noemi, Peach, Megan L., Blumberg, Peter M., Keck, Gary E.

Journal:

Journal of Organic Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2016

3

Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1

Gary E. Keck, Yam B. Poudel, Arnab Rudra, Jeffrey C. Stephens, Noemi Kedei, Nancy E. Lewin, Megan L. Peach, Peter M. Blumberg

Journal:

Angewandte Chemie

Année:

2010

Langue:

english

Fichier:

PDF, 521 KB

english, 2010

4

Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1

Gary E. Keck, Yam B. Poudel, Arnab Rudra, Jeffrey C. Stephens, Noemi Kedei, Nancy E. Lewin, Megan L. Peach, Peter M. Blumberg

Journal:

Angewandte Chemie International Edition

Année:

2010

Langue:

english

Fichier:

PDF, 540 KB

english, 2010

5

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP

Garcia, Lia C., Donadío, Lucia Gandolfi, Mann, Ella, Kolusheva, Sofiya, Kedei, Noemi, Lewin, Nancy E., Hill, Colin S., Kelsey, Jessica S., Yang, Jing, Esch, Timothy E., Santos, Marina, Peach, Megan L.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2014

6

Absolute quantitation of endogenous proteins with precision and accuracy using a capillary Western system

Chen, Jin-Qiu, Heldman, Madeleine R., Herrmann, Michelle A., Kedei, Noemi, Woo, Wonhee, Blumberg, Peter M., Goldsmith, Paul K.

Journal:

Analytical Biochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 857 KB

english, 2013

7

Synthesis of a des -B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core

Kraft, Matthew B., Poudel, Yam B., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M., Keck, Gary E.

Journal:

Journal of the American Chemical Society

Année:

2014

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2014

8

Synthesis of seco -B-Ring Bryostatin Analogue WN-1 via C–C Bond-Forming Hydrogenation: Critical Contribution of the B-Ring in Determining Bryostatin-like and Phorbol 12-Myristate 13-Acetate-like Properties

Andrews, Ian P., Ketcham, John M., Blumberg, Peter M., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Krische, Michael J.

Journal:

Journal of the American Chemical Society

Année:

2014

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2014

9

Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective Biological Activities

Duan, Dehui, Sigano, Dina M., Kelley, James A., Lai, Christopher C., Lewin, Nancy E., Kedei, Noemi, Peach, Megan L., Lee, Jeewoo, Abeyweera, Thushara P., Rotenberg, Susan A., Kim, Hee, Kim, Young Ho,

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 3.49 MB

english, 2008

10

Molecular Basis for Failure of "Atypical" C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

Geczy, T., Peach, M. L., El Kazzouli, S., Sigano, D. M., Kang, J.-H., Valle, C. J., Selezneva, J., Woo, W., Kedei, N., Lewin, N. E., Garfield, S. H., Lim, L., Mannan, P., Marquez, V. E., Blumberg, P.

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 5.41 MB

english, 2012

11

Wealth of Opportunity - The C1 Domain as a Target for Drug Development

Blumberg, P., Kedei, N., Lewin, N., Yang, D., Czifra, G., Pu, Y., Peach, M., Marquez, V

Journal:

Current Drug Targets

Année:

2008

Langue:

english

Fichier:

PDF, 483 KB

english, 2008

12

Does budget deficit affect short and long term interest rates differently?

Nwosa, Philip Ifeakachukwu, Ibas, Catherine Kedei

Journal:

International Journal of Economics and Business Research

Année:

2014

Langue:

english

Fichier:

PDF, 296 KB

english, 2014

13

Critical role of Trp-588 of presynaptic Munc13-1 for ligand binding and membrane translocation

Das, Joydip, Kedei, Noemi, Kelsey, Jessica S, You, Youngki, Pany, Satyabrata, Mitchell, Gary A, Lewin, Nancy E., Blumberg, Peter M.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.42 MB

english, 2017

14

Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities

Or Raifman, Dr. Sofiya Kolusheva, Dr. Said El Kazzouli, Dr. Dina M. Sigano, Dr. Noemi Kedei, Dr. Nancy E. Lewin, Ruben Lopez-Nicolas, Ana Ortiz-Espin, Juan C. Gomez-Fernandez, Dr. Peter M. Blumberg, D

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 488 KB

english, 2010

15

Inside Cover: Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities (ChemBioChem 14/2010)

Or Raifman, Dr. Sofiya Kolusheva, Dr. Said El Kazzouli, Dr. Dina M. Sigano, Dr. Noemi Kedei, Dr. Nancy E. Lewin, Ruben Lopez-Nicolas, Ana Ortiz-Espin, Juan C. Gomez-Fernandez, Dr. Peter M. Blumberg, D

Journal:

Année:

2010

Fichier:

PDF, 618 KB

2010

16

Some Phorbol Esters Might Partially Resemble Bryostatin 1 in their Actions on LNCaP Prostate Cancer Cells and U937 Leukemia Cells

Dr. Noemi Kedei, Emanuel Lubart, Nancy E. Lewin, Dr. Andrea Telek, Langston Lim, Poonam Mannan, Dr. Susan H. Garfield, Matthew B. Kraft, Prof. Dr. Gary E. Keck, Dr. Sofiya Kolusheva, Prof. Dr. Raz Jel

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 768 KB

english, 2011

17

N-Methyl-Substituted Fluorescent DAG–Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity

Noga Gal, Dr. Sofiya Kolusheva, Dr. Noemi Kedei, Dr. Andrea Telek, Taiyabah A. Naeem, Nancy E. Lewin, Langston Lim, Poonam Mannan, Susan H. Garfield, Dr. Saïd El Kazzouli, Dr. Dina M. Sigano, Dr. Vict

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 6.65 MB

english, 2011

18

Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities

Or Raifman, Sofiya Kolusheva, Maria J. Comin, Noemi Kedei, Nancy E. Lewin, Peter M. Blumberg, Victor E. Marquez, Raz Jelinek

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 754 KB

english, 2010

19

RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma

Yang, D, Tao, J, Li, L, Kedei, N, Tóth, Z E, Czap, A, Velasquez, J F, Mihova, D, Michalowski, A M, Yuspa, S H

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 906 KB

english, 2011

20

The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line

Noemi Kedei, Andrea Telek, Alexandra Czap, Emanuel S. Lubart, Gabriella Czifra, Dazhi Yang, Jinqiu Chen, Tyler Morrison, Paul K. Goldsmith, Langston Lim, Poonam Mannan, Susan H. Garfield, Matthew B. K

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2011

21

Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity

Gary E. Keck, Yam B. Poudel, Arnab Rudra, Jeffrey C. Stephens, Noemi Kedei, Nancy E. Lewin, Peter M. Blumberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2012

22

Lack of Induction of Tissue Transglutaminase But Activation of the Preexisting Enzyme in c-Myc-Induced Apoptosis of CHO Cells

Zoltán Balajthy, Noémi Kedei, László Nagy, Peter J.A. Davies, László Fésüs

Journal:

Biochemical and Biophysical Research Communications

Année:

1997

Langue:

english

Fichier:

PDF, 390 KB

english, 1997

23

Degradation of cells dying by apoptosis leads to accumulation of ε(γ-glutamyl)lysine isodipeptide in culture fluid and blood

Laszlo Fesus, Edit Tarcsa, Noemi Kedei, Francesco Autuori, Mauro Piacentini

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 774 KB

english, 1991

24

Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1

Attila Tóth, Yun Wang, Noémi Kedei, Richard Tran, Larry V. Pearce, Sang-Uk Kang, Mi-Kyung Jin, Hyun-Kyung Choi, Jeewoo Lee, Peter M. Blumberg

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 369 KB

english, 2005

25

Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain

Attila Tóth, Judit Boczán, Noémi Kedei, Erzsébet Lizanecz, Zsolt Bagi, Zoltán Papp, István Édes, László Csiba, Peter M. Blumberg

Journal:

Molecular Brain Research

Année:

2005

Langue:

english

Fichier:

PDF, 499 KB

english, 2005

26

Thapsigargin binds to and inhibits the cloned vanilloid receptor-1

Attila Tóth, Noémi Kedei, Tamás Szabó, Yun Wang, Peter M Blumberg

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 163 KB

english, 2002

27

Differential expression of tissue transglutaminase during in vivo apoptosis of thymocytes induced via distinct signalling pathways

Zsuzsa Szondy, Peter Molnar, Zoltán Nemes, Michael Boyiadzis, Noémi Kedei, Réka Tóth, László Fésüs

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 1001 KB

english, 1997

28

Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat

Attila Tóth, Noémi Kedei, Yun Wang, Peter M. Blumberg

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 198 KB

english, 2003

29

Characterization of the Interaction of Ingenol 3-Angelate with Protein Kinase C

Journal:

Cancer Research

Année:

2004

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2004

30

Biological Profile of the Less Lipophilic and Synthetically More Accessible Bryostatin 7 Closely Resembles That of Bryostatin 1

Kedei, Noemi, Lewin, Nancy E., Géczy, Tamás, Selezneva, Julia, Braun, Derek C., Chen, Jinqiu, Herrmann, Michelle A., Heldman, Madeleine R., Lim, Langston, Mannan, Poonam, Garfield, Susan H., Poudel, Y

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2013

31

Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action

Kedei, N., Telek, A., Michalowski, A.M., Kraft, M.B., Li, W., Poudel, Y.B., Rudra, A., Petersen, M.E., Keck, G.E., Blumberg, P.M.

Journal:

Biochemical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2013

32

Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-Alikes That Mimic Phorbol Ester Function

Keck, Gary E., Kraft, Matthew B., Truong, Anh P., Li, Wei, Sanchez, Carina C., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 151 KB

english, 2008

33

The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses

Keck, Gary E., Li, Wei, Kraft, Matthew B., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.

Journal:

Organic Letters

Année:

2009

Langue:

english

Fichier:

PDF, 439 KB

english, 2009

34

Self-Assembly and Lipid Interactions of Diacylglycerol Lactone Derivatives Studied at the Air/Water Interface

Philosof-Mazor, Liron, Volinsky, Roman, Comin, Maria J., Lewin, Nancy E., Kedei, Noemi, Blumberg, Peter M., Marquez, Victor E., Jelinek, Raz

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2008

35

Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters

Keck, Gary E., Poudel, Yam B., Welch, Dennie S., Kraft, Matthew B., Truong, Anh P., Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.

Journal:

Organic Letters

Année:

2009

Langue:

english

Fichier:

PDF, 328 KB

english, 2009

36

Conformationally Constrained Analogues of Diacylglycerol (DAG). 31. Modulation of the Biological Properties of Diacylgycerol Lactones (DAG-lactones) Containing Rigid-Rod Acyl Groups Separated from the Core Lactone by Spacer Units of Different Lengths

Comin, Maria J., Czifra, Gabriella, Kedei, Noemi, Telek, Andrea, Lewin, Nancy E., Kolusheva, Sofiya, Velasquez, Julia F., Kobylarz, Ryan, Jelinek, Raz, Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2009

37

Conformationally Constrained Analogues of Diacylglycerol (DAG). 27. Modulation of Membrane Translocation of Protein Kinase C (PKC) Isozymes α and δ by Diacylglycerol Lactones (DAG- l actones) Containing Rigid-Rod Acyl Groups

Malolanarasimhan, Krishnan, Kedei, Noemi, Sigano, Dina M., Kelley, James A., Lai, Christopher C., Lewin, Nancy E., Surawski, Robert J., Pavlyukovets, Vladimir A., Garfield, Susan H., Wincovitch, Steph

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 521 KB

english, 2007

38

Molecular Systems Pharmacology: Isoelectric Focusing Signature of Protein Kinase Cδ Provides an Integrated Measure of Its Modulation in Response to Ligands

Kedei, Noemi, Chen, Jin-Qiu, Herrmann, Michelle A., Telek, Andrea, Goldsmith, Paul K., Petersen, Mark E., Keck, Gary E., Blumberg, Peter M.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 6.75 MB

english, 2014

39

Evodiamine functions as an agonist for the vanilloid receptor TRPV1

Pearce, Larry V., Petukhov, Pavel A., Szabo, Tamas, Kedei, Noemi, Bizik, Fero, Kozikowski, Alan P., Blumberg, Peter M.

Journal:

Organic & Biomolecular Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2004

40

Charge Density Influences C1 Domain Ligand Affinity and Membrane Interactions

Kelsey, Jessica S., Geczy, Tamas, Lewin, Nancy E., Kedei, Noemi, Hill, Colin S., Selezneva, Julia S., Valle, Christopher J., Woo, Wonhee, Gorshkova, Inna, Blumberg, Peter M.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.79 MB

english, 2014

41

A Phospholipase C- 1-Independent, RasGRP1-ERK-Dependent Pathway Drives Lymphoproliferative Disease in Linker for Activation of T Cells-Y136F Mutant Mice

Kortum, R. L., Rouquette-Jazdanian, A. K., Miyaji, M., Merrill, R. K., Markegard, E., Pinski, J. M., Wesselink, A., Nath, N. N., Alexander, C. P., Li, W., Kedei, N., Roose, J. P., Blumberg, P. M., Sam

Journal:

The Journal of Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2013

42

Characterization of the Differential Roles of the Twin C1a and C1b Domains of Protein Kinase C

Pu, Y., Garfield, S. H., Kedei, N., Blumberg, P. M.

Journal:

Journal of Biological Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2009

43

Characterization of the Interaction of Phorbol Esters with the C1 Domain of MRCK (Myotonic Dystrophy Kinase-related Cdc42 Binding Kinase) /

Choi, S. H., Czifra, G., Kedei, N., Lewin, N. E., Lazar, J., Pu, Y., Marquez, V. E., Blumberg, P. M.

Journal:

Journal of Biological Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 460 KB

english, 2008

44

A Novel Diacylglycerol-lactone Shows Marked Selectivity in Vitro among C1 Domains of Protein Kinase C (PKC) Isoforms and as Well as Selectivity for RasGRP Compared with PKC

Pu, Y., Perry, N. A., Yang, D., Lewin, N. E., Kedei, N., Braun, D. C., Choi, S. H., Blumberg, P. M., Garfield, S. H., Stone, J. C., Duan, D., Marquez, V. E.

Journal:

Journal of Biological Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2005

45

Interaction between Protein Kinase C and the Vanilloid Receptor Type 1

Wang, Y., Kedei, N., Wang, M., Wang, Q. J., Huppler, A. R., Toth, A., Tran, R., Blumberg, P. M.

Journal:

Journal of Biological Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 951 KB

english, 2004

46

Analysis of the Native Quaternary Structure of Vanilloid Receptor 1

Journal:

Journal of Biological Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 309 KB

english, 2001

47

Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

Rahman, Ghazi M., Shanker, Sreejesh, Lewin, Nancy E., Kedei, Noemi, Hill, Colin S., Prasad, B. V. Venkataram, Blumberg, Peter M., Das, Joydip

Journal:

Biochemical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2013

48

RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype

Yang, D., Kedei, N., Li, L., Tao, J., Velasquez, J. F., Michalowski, A. M., Toth, B. I., Marincsak, R., Varga, A., Biro, T., Yuspa, S. H., Blumberg, P. M.

Journal:

Cancer Research

Année:

2010

Langue:

english

Fichier:

PDF, 689 KB

english, 2010

49

Protein Cross-linking Mediated by Tissue Transglutaminase Correlates with the Maturation of Extracellular Matrices During Lung Development

Schittny, Johannes C., Paulsson, Mats, Vallan, Claudio, Burri, Peter H., Kedei, Noemi, Aeschlimann, Daniel

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

1997

Langue:

english

Fichier:

PDF, 666 KB

english, 1997

50

Structural basis for the failure of the C1 domain of RasGRP2 to bind phorbol ester with high affinity

Czikora, Agnes, Lundberg, Daniel J., Abramovitz, Adelle, Lewin, Nancy E., Kedei, Noemi, Peach, Megan L., Zhou, Xiaoling, Merritt, Raymond C., Craft, Elizabeth A., Braun, Derek C., Blumberg, Peter M.

Journal:

Journal of Biological Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2016